Donor-derived cell-free DNA as a diagnostic tool in transplantation

Donor-derived cell-free DNA as a diagnostic tool in transplantation

There is a need to improve personalized immunosuppression in organ transplantation to reduce premature graft loss. Biomarkers are needed to better detect rejection, asymptomatic graft injury, and under-immunosuppression. Assessment of minimal necessary exposure to guide tapering and prevent immune a...

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Bibliographic Details
Main Authors: Michael Oellerich, Klemens Budde, Bilgin Osmanodja, Kirsten Bornemann-Kolatzki, Julia Beck, Ekkehard Schütz, Philip D. Walson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Genetics
Subjects:
donor-derived cell-free DNA
transplant surveillance
graft injury
personalized immunosuppression
liquid biopsy
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2022.1031894/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2022.1031894/full

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