Initial clinical validation of a hybrid in silico—in vitro cardiorespiratory simulator for comprehensive testing of mechanical circulatory support systems
Simulators are expected to assume a prominent role in the process of design—development and testing of cardiovascular medical devices. For this purpose, simulators should capture the complexity of human cardiorespiratory physiology in a realistic way. High fidelity simulations of pathophysiology do...
Main Authors: | Libera Fresiello, Kavitha Muthiah, Kaatje Goetschalckx, Christopher Hayward, Maria Rocchi, Maxime Bezy, Jo P. Pauls, Bart Meyns, Dirk W. Donker, Krzysztof Zieliński |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-10-01
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Series: | Frontiers in Physiology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2022.967449/full |
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