The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network

The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network

Genome-Wide Association Studies (GWAS) and subsequent fine-mapping studies (>50) have implicated single nucleotide polymorphisms (SNPs) located at the CCDC170/C6ORF97-ESR1 locus (6q25.1) as being associated with the risk of breast cancer. Surprisingly, our analysis using genome-wide differential...

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Bibliographic Details
Main Authors: Pengtao Jiang, Yueran Li, Andrey Poleshko, Valentina Medvedeva, Natalia Baulina, Yongchao Zhang, Yan Zhou, Carolyn M. Slater, Trinity Pellegrin, Jason Wasserman, Michael Lindy, Andrey Efimov, Mary Daly, Richard A. Katz, Xiaowei Chen
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:EBioMedicine
Subjects:
CCDC170/C6ORF97
Golgi-associated microtubules
Tubulin acetylation
Polarized cell migration
Genome-wide association studies (GWAS)
Differential allele specific expression (DASE)
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417302591

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http://www.sciencedirect.com/science/article/pii/S2352396417302591

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