ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury

Abstract Mitochondria dysfunction contributes to acute liver injuries, and mitochondrial regulators, such as PGC-1α and MCJ, affect liver regeneration. Therefore, identification of mitochondrial modulators may pave the way for developing therapeutic strategies. Here, ZHX2 is identified as a mitochon...

Full description

Bibliographic Details
Main Authors: Yankun Zhang, Yuchen Fan, Huili Hu, Xiaohui Zhang, Zehua Wang, Zhuanchang Wu, Liyuan Wang, Xiangguo Yu, Xiaojia Song, Peng Xiang, Xiaodong Zhang, Tixiao Wang, Siyu Tan, Chunyang Li, Lifen Gao, Xiaohong Liang, Shuijie Li, Nailin Li, Xuetian Yue, Chunhong Ma
Format: Article
Language:English
Published: Nature Portfolio 2023-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-43439-0