Impact of the Pd<sub>2</sub>Spm (Spermine) Complex on the Metabolism of Triple-Negative Breast Cancer Tumors of a Xenograft Mouse Model

Impact of the Pd<sub>2</sub>Spm (Spermine) Complex on the Metabolism of Triple-Negative Breast Cancer Tumors of a Xenograft Mouse Model

The interest in palladium(II) compounds as potential new anticancer drugs has increased in recent years, due to their high toxicity and acquired resistance to platinum(II)-derived agents, namely cisplatin. In fact, palladium complexes with biogenic polyamines (e.g., spermine, Pd<sub>2</sub&...

Full description

Bibliographic Details
Main Authors: Tatiana J. Carneiro, Rita Araújo, Martin Vojtek, Salomé Gonçalves-Monteiro, Ana L. M. Batista de Carvalho, Maria Paula M. Marques, Carmen Diniz, Ana M. Gil
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
platinum(II)
palladium(II)
spermine
cisplatin
human triple-negative breast cancer
xenografts
Online Access:https://www.mdpi.com/1422-0067/22/19/10775

Internet

https://www.mdpi.com/1422-0067/22/19/10775

Similar Items