The telomere complex and the origin of the cancer stem cell
Abstract Exquisite regulation of telomere length is essential for the preservation of the lifetime function and self-renewal of stem cells. However, multiple oncogenic pathways converge on induction of telomere attrition or telomerase overexpression and these events can by themselves trigger maligna...
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| Format: | Article |
| Language: | English |
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BMC
2021-11-01
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| Series: | Biomarker Research |
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| Online Access: | https://doi.org/10.1186/s40364-021-00339-z |