Integration of scRNA-Seq and bulk RNA-Seq uncover perturbed immune cell types and pathways of Kawasaki disease

Integration of scRNA-Seq and bulk RNA-Seq uncover perturbed immune cell types and pathways of Kawasaki disease

IntroductionKawasaki disease (KD) is an acute febrile illness primarily affecting children and characterized by systemic inflammation and vasculitis that can lead to coronary artery complications. The aim of this study was to gain a comprehensive understanding of immune dysregulation in KD.MethodsTo...

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Bibliographic Details
Main Authors: Naixin Cao, Huayi Ouyang, Xing Zhang, Yuanyuan Xu, Jun Li, Yanfei Chen
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-09-01
Series:Frontiers in Immunology
Subjects:
KD
immune dysregulation
ScRNA-seq
WGCNA
immunopathogenesis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1259353/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2023.1259353/full

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