Network-Based Prediction of Side Effects of Repurposed Antihypertensive Sartans against COVID-19 via Proteome and Drug-Target Interactomes

Network-Based Prediction of Side Effects of Repurposed Antihypertensive Sartans against COVID-19 via Proteome and Drug-Target Interactomes

The potential of targeting the Renin-Angiotensin-Aldosterone System (RAAS) as a treatment for the coronavirus disease 2019 (COVID-19) is currently under investigation. One way to combat this disease involves the repurposing of angiotensin receptor blockers (ARBs), which are antihypertensive drugs, b...

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Bibliographic Details
Main Authors: Despoina P. Kiouri, Charalampos Ntallis, Konstantinos Kelaidonis, Massimiliano Peana, Sotirios Tsiodras, Thomas Mavromoustakos, Alessandro Giuliani, Harry Ridgway, Graham J. Moore, John M. Matsoukas, Christos T. Chasapis
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Proteomes
Subjects:
angiotensin receptor blockers
Sartans
coronavirus disease 19
angiotensin-converting enzyme 2
protein–protein interaction networks
drug–drug interaction prediction
Online Access:https://www.mdpi.com/2227-7382/11/2/21

Internet

https://www.mdpi.com/2227-7382/11/2/21

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