Discovering vesicle traffic network constraints by model checking.

A eukaryotic cell contains multiple membrane-bound compartments. Transport vesicles move cargo between these compartments, just as trucks move cargo between warehouses. These processes are regulated by specific molecular interactions, as summarized in the Rothman-Schekman-Sudhof model of vesicle tra...

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Bibliographic Details
Main Authors: Ankit Shukla, Arnab Bhattacharyya, Lakshmanan Kuppusamy, Mandayam Srivas, Mukund Thattai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5500374?pdf=render