Predicting Objective Response Rate (ORR) in Immune Checkpoint Inhibitor (ICI) Therapies with Machine Learning (ML) by Combining Clinical and Patient-Reported Data

Predicting Objective Response Rate (ORR) in Immune Checkpoint Inhibitor (ICI) Therapies with Machine Learning (ML) by Combining Clinical and Patient-Reported Data

ICIs are a standard of care in several malignancies; however, according to overall response rate (ORR), only a subset of eligible patients benefits from ICIs. Thus, an ability to predict ORR could enable more rational use. In this study a ML-based ORR prediction model was built, with patient-reporte...

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Bibliographic Details
Main Authors: Sanna Iivanainen, Jussi Ekström, Henri Virtanen, Vesa V. Kataja, Jussi P. Koivunen
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Applied Sciences
Subjects:
ePRO
machine learning
prediction model
irAE
immune checkpoint inhibitor
prognosis
Online Access:https://www.mdpi.com/2076-3417/12/3/1563

Internet

https://www.mdpi.com/2076-3417/12/3/1563

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