Gentiana lutea attenuates hepatotoxicity induced by ketoconazole in rats by fortifying the cellular antioxidant defense system

Abstract Background Ketoconazole (KET) is a broad-spectrum antifungal drug that has been reported to induce hepatotoxicity in humans and animals. Methods The safe guarding response of Gentiana extract (GEN) against KET-induced hepatotoxicity was investigated in this study using male Wistar rats. GEN...

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Bibliografische gegevens
Hoofdauteurs: Alaaeldin Ahmed Hamza, Mona Gamel, Ali Abdalla, Youssef Abdalla, Amr Amin
Formaat: Artikel
Taal:English
Gepubliceerd in: SpringerOpen 2023-01-01
Reeks:Journal of Basic and Applied Zoology
Onderwerpen:
Online toegang:https://doi.org/10.1186/s41936-022-00321-7