Transmitted HIV-1 is more virulent in heterosexual individuals than men-who-have-sex-with-men

Transmission bottlenecks introduce selection pressures on HIV-1 that vary with the mode of transmission. Recent studies on small cohorts have suggested that stronger selection pressures lead to fitter transmitted/founder (T/F) strains. Manifestations of this selection bias at the population level ha...

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Bibliographic Details
Main Authors: Ananthu James, Narendra M. Dixit
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-03-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8912199/?tool=EBI