DNA Methylation of Human Choline Kinase Alpha Promoter-Associated CpG Islands in MCF-7 Cells

DNA Methylation of Human Choline Kinase Alpha Promoter-Associated CpG Islands in MCF-7 Cells

Choline kinase (CK) is the enzyme catalyzing the first reaction in CDP-choline pathway for the biosynthesis of phosphatidylcholine. Higher expression of the α isozyme of CK has been implicated in carcinogenesis, and inhibition or downregulation of CKα (CHKA) is a promising anticancer approach. This...

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Bibliographic Details
Main Authors: Siti Aisyah Faten Mohamed Sa’dom, Sweta Raikundalia, Shaharum Shamsuddin, Wei Cun See Too, Ling Ling Few
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Genes
Subjects:
DNA methylation
promoter
CpG island
<i>ckα</i>
cancer
Online Access:https://www.mdpi.com/2073-4425/12/6/853

Internet

https://www.mdpi.com/2073-4425/12/6/853

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