DamID in C. elegans reveals longevity‐associated targets of DAF‐16/FoxO

DamID in C. elegans reveals longevity‐associated targets of DAF‐16/FoxO

Insulin/IGF‐1 signaling controls metabolism, stress resistance and aging in Caenorhabditis elegans by regulating the activity of the DAF‐16/FoxO transcription factor (TF). However, the function of DAF‐16 and the topology of the transcriptional network that it crowns remain unclear. Using chromatin p...

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Bibliographic Details
Main Authors: Eugene Schuster, Joshua J McElwee, Jennifer M A Tullet, Ryan Doonan, Filip Matthijssens, John S Reece‐Hoyes, Ian A Hope, Jacques R Vanfleteren, Janet M Thornton, David Gems
Format: Article
Language:English
Published: Springer Nature 2010-01-01
Series:Molecular Systems Biology
Subjects:
aging
C. elegans
DAF‐16/FoxO
DamID chromatin profiling
transcriptional networks
Online Access:https://doi.org/10.1038/msb.2010.54

Internet

https://doi.org/10.1038/msb.2010.54

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