A flavonoid, luteolin, cripples HIV-1 by abrogation of tat function.

Despite the effectiveness of combination antiretroviral treatment (cART) against HIV-1, evidence indicates that residual infection persists in different cell types. Intensification of cART does not decrease the residual viral load or immune activation. cART restricts the synthesis of infectious viru...

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Bibliographic Details
Main Authors: Rajeev Mehla, Shalmali Bivalkar-Mehla, Ashok Chauhan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3227592?pdf=render