Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula

Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula

The mechanism underlying caffeine consumption inversely correlation with depression is unclear. Here, authors identified adenosine A2A receptor in the lateral septum mediating depressive symptoms via direct outputs to the habenula and the hypothalamus.

Bibliographic Details
Main Authors: Muran Wang, Peijun Li, Zewen Li, Beatriz S. da Silva, Wu Zheng, Zhenghua Xiang, Yan He, Tao Xu, Cristina Cordeiro, Lu Deng, Yuwei Dai, Mengqian Ye, Zhiqing Lin, Jianhong Zhou, Xuzhao Zhou, Fenfen Ye, Rodrigo A. Cunha, Jiangfan Chen, Wei Guo
Format: Article
Language:English
Published: Nature Portfolio 2023-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-37601-x

Internet

https://doi.org/10.1038/s41467-023-37601-x

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