Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula
The mechanism underlying caffeine consumption inversely correlation with depression is unclear. Here, authors identified adenosine A2A receptor in the lateral septum mediating depressive symptoms via direct outputs to the habenula and the hypothalamus.
Bibliographic Details
| Main Authors: |
Muran Wang,
Peijun Li,
Zewen Li,
Beatriz S. da Silva,
Wu Zheng,
Zhenghua Xiang,
Yan He,
Tao Xu,
Cristina Cordeiro,
Lu Deng,
Yuwei Dai,
Mengqian Ye,
Zhiqing Lin,
Jianhong Zhou,
Xuzhao Zhou,
Fenfen Ye,
Rodrigo A. Cunha,
Jiangfan Chen,
Wei Guo |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Portfolio
2023-04-01
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| Series: | Nature Communications
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| Online Access: | https://doi.org/10.1038/s41467-023-37601-x
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