Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis.

Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis.

Simultaneous multiplex mutation of large gene families using Cas9 has the potential to revolutionize agriculture and plant sciences. The targeting of multiple genomic sites at once raises concerns about the efficiency and specificity in targeting. The model Arabidopsis thaliana is widely used in bas...

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Bibliographic Details
Main Authors: Brenda A Peterson, David C Haak, Marc T Nishimura, Paulo J P L Teixeira, Sean R James, Jeffery L Dangl, Zachary L Nimchuk
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5021288?pdf=render

Internet

http://europepmc.org/articles/PMC5021288?pdf=render

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