Agmatine reduces chlorpromazine prooxidant effects in rat hippocampus and striatum

Agmatine reduces chlorpromazine prooxidant effects in rat hippocampus and striatum

The use of the antidepressant drug chlorpromazine (CPZ) is linked to the occurrence of oxidative stress in some brain structures. Thus, overcoming the side effects of CPZ is of great importance. Because agmatine (AGM) can act as a free radical scavenger, it is an interesting compound as an adjunct t...

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Bibliographic Details
Main Authors: Dejanović Bratislav, Begović-Kuprešanin Vesna, Stevanović Ivana, Lavrnja Irena, Šošić-Jurjević Branka, Ninković Milica, Trifunović Svetlana
Format: Article
Language:English
Published: University of Belgrade, University of Novi Sad 2021-01-01
Series:Archives of Biological Sciences
Subjects:
chlorpromazine
agmatine
oxidative stress
hippocampus
striatum
Online Access:http://www.doiserbia.nb.rs/img/doi/0354-4664/2021/0354-46642100028D.pdf

Internet

http://www.doiserbia.nb.rs/img/doi/0354-4664/2021/0354-46642100028D.pdf

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