OCOSO2: study protocol for a single-blinded, multicentre, randomised controlled trial assessing a central venous oxygen saturation-based goal-directed therapy to reduce postoperative complications in high-risk patients after elective major surgery

OCOSO2: study protocol for a single-blinded, multicentre, randomised controlled trial assessing a central venous oxygen saturation-based goal-directed therapy to reduce postoperative complications in high-risk patients after elective major surgery

Abstract Background Fluid loading-based goal-directed therapy is a cornerstone of anaesthesia management in major surgery. Its widespread application has contributed to a significant improvement in perioperative morbidity and mortality. In theory, only hypovolemic patients should receive fluid thera...

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Bibliographic Details
Main Authors: Bruno Pastene, Matthieu Bernat, Karine Baumstark, Karine Bezulier, Yann Gricourt, Jean-Manuel De Guibert, Aude Charvet, Manon Colin, Marc Leone, Laurent Zieleskiewicz
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Trials
Online Access:https://doi.org/10.1186/s13063-023-07689-z

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https://doi.org/10.1186/s13063-023-07689-z

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