Origins of truncated supplementary capsid proteins in rAAV8 vectors produced with the baculovirus system.

The ability to produce large quantities of recombinant Adeno-Associated Virus (rAAV) vectors is an important factor for the development of gene therapy-based medicine. The baculovirus/insect cell expression system is one of the major systems for large scale rAAV production. So far, most technologica...

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Bibliographic Details
Main Authors: Lionel Galibert, Adrien Savy, Yohann Dickx, Delphine Bonnin, Bérangère Bertin, Isidore Mushimiyimana, Monique M van Oers, Otto-Wilhelm Merten
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6237368?pdf=render