Maintenance of telomere length in AML

Abstract: The importance of telomere length to human health, aging, and cancer continues to be underappreciated. This review examines some basics of telomere biology and relates how telomere function, telomerase activity, and mutations in TERC or TERT are involved in bone marrow failure, leukemias,...

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Bibliographic Details
Main Author: Peter M. Lansdorp
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Blood Advances
Online Access:http://www.sciencedirect.com/science/article/pii/S2473952920301191