Endothelial alpha globin is a nitrite reductase

Endothelial alpha globin is a nitrite reductase

In mammals, hypoxia causes dilation of small arteries for increased metabolic demand. Keller et al used novel transgenic mice to show alpha hemoglobin in endothelium, once thought only in red blood cells, can regulate hypoxic-mediated dilation.

Detalles Bibliográficos
Autores principales:	T. C. Stevenson Keller, Christophe Lechauve, Alexander S. Keller, Gilson Brás Broseghini-Filho, Joshua T. Butcher, Henry R. Askew Page, Aditi Islam, Zhe Yin Tan, Leon J. DeLalio, Steven Brooks, Poonam Sharma, Kwangseok Hong, Wenhao Xu, Alessandra Simão Padilha, Claire A. Ruddiman, Angela K. Best, Edgar Macal, Daniel B. Kim-Shapiro, George Christ, Zhen Yan, Miriam M. Cortese-Krott, Karina Ricart, Rakesh Patel, Timothy P. Bender, Swapnil K. Sonkusare, Mitchell J. Weiss, Hans Ackerman, Linda Columbus, Brant E. Isakson
Formato:	Artículo
Lenguaje:	English
Publicado:	Nature Portfolio 2022-10-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-022-34154-3

Internet

https://doi.org/10.1038/s41467-022-34154-3