Prader-Willi Syndrome: The Disease that Opened up Epigenomic-Based Preemptive Medicine

Prader-Willi Syndrome: The Disease that Opened up Epigenomic-Based Preemptive Medicine

Prader-Willi syndrome (PWS) is a congenital neurodevelopmental disorder caused by loss of function of paternally expressed genes on chromosome 15 due to paternal deletion of 15q11–q13, maternal uniparental disomy for chromosome 15, or an imprinting mutation. We previously developed a DNA methylation...

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Bibliographic Details
Main Authors: Takeo Kubota, Kunio Miyake, Natsuyo Hariya, Vuong Tran Nguyen Quoc, Kazuki Mochizuki
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Diseases
Subjects:
Prader-Willi syndrome
genomic imprinting
epigenetics
epigenomics
diagnosis
intervention
preemptive medicine
Online Access:http://www.mdpi.com/2079-9721/4/1/15

Internet

http://www.mdpi.com/2079-9721/4/1/15

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