Cancer Immunotherapy by Blocking Immune Checkpoints on Innate Lymphocytes

Cancer Immunotherapy by Blocking Immune Checkpoints on Innate Lymphocytes

Immune checkpoints refer to a plethora of inhibitory pathways of the immune system that play a crucial role in maintaining self-tolerance and in tuning the duration and amplitude of physiological immune responses to minimize collateral tissue damages. The breakdown of this delicate balance leads to...

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Bibliographic Details
Main Authors: Silvia Pesce, Sara Trabanelli, Clara Di Vito, Marco Greppi, Valentina Obino, Fabio Guolo, Paola Minetto, Matteo Bozzo, Michela Calvi, Elisa Zaghi, Simona Candiani, Roberto Massimo Lemoli, Camilla Jandus, Domenico Mavilio, Emanuela Marcenaro
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Cancers
Subjects:
natural killer cells
innate lymphoid cells
immune checkpoint
immunotherapy
KIR
PD-1
Online Access:https://www.mdpi.com/2072-6694/12/12/3504

Internet

https://www.mdpi.com/2072-6694/12/12/3504

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