Hepatitis delta virus RNA decline post-inoculation in human NTCP transgenic mice is biphasic

Hepatitis delta virus RNA decline post-inoculation in human NTCP transgenic mice is biphasic

ABSTRACT Chronic infection with hepatitis B and delta viruses (HDV) is the most serious form of viral hepatitis due to more severe manifestations of an accelerated progression to liver fibrosis, cirrhosis, and hepatocellular carcinoma. We characterized early HDV kinetics post-inoculation and incorpo...

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Bibliographic Details
Main Authors: Stephanie Maya, Leeor Hershkovich, E. Fabian Cardozo-Ojeda, Elham Shirvani-Dastgerdi, Jay Srinivas, Louis Shekhtman, Susan L. Uprichard, Andrew R. Berneshawi, Thomas R. Cafiero, Harel Dahari, Alexander Ploss
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:mBio
Subjects:
viral hepatitis
hepatitis delta virus
hepatitis B virus
mathematical modeling
animal model
Online Access:https://journals.asm.org/doi/10.1128/mbio.01008-23

Internet

https://journals.asm.org/doi/10.1128/mbio.01008-23

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