Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes
<p>Abstract</p> <p/> <p>Type 1 diabetes occurs when self-reactive T lymphocytes destroy the insulin-producing islet β cells of the pancreas. The defects causing this disease have often been assumed to occur exclusively in the immune system. We present evidence that genetic va...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-01-01
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| Series: | Biology Direct |
| Online Access: | http://www.biology-direct.com/content/2/1/5 |