Underestimated pyrazinamide resistance may compromise outcomes of pyrazinamide containing regimens for treatment of drug susceptible and multi-drug-resistant tuberculosis in Tanzania

Underestimated pyrazinamide resistance may compromise outcomes of pyrazinamide containing regimens for treatment of drug susceptible and multi-drug-resistant tuberculosis in Tanzania

Abstract Background Tuberculosis (TB) is the leading cause of death from an infectious disease and the roll-out of rapid molecular diagnostics for rifampin resistance has resulted in a steady rise in the number of patients with multidrug-resistant (MDR)-TB referred for treatment. Pyrazinamide is use...

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Bibliographic Details
Main Authors: Saumu Pazia Juma, Athanasia Maro, Suporn Pholwat, Stellah G. Mpagama, Jean Gratz, Alphonse Liyoyo, Eric R. Houpt, Gibson S. Kibiki, Blandina T. Mmbaga, Scott K. Heysell
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Infectious Diseases
Online Access:http://link.springer.com/article/10.1186/s12879-019-3757-1

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http://link.springer.com/article/10.1186/s12879-019-3757-1

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