Treatment Combining CD200 Immune Checkpoint Inhibitor and Tumor-Lysate Vaccination after Surgery for Pet Dogs with High-Grade Glioma

Treatment Combining CD200 Immune Checkpoint Inhibitor and Tumor-Lysate Vaccination after Surgery for Pet Dogs with High-Grade Glioma

Recent advances in immunotherapy have included inhibition of immune checkpoint proteins in the tumor microenvironment and tumor lysate-based vaccination strategies. We combined these approaches in pet dogs with high-grade glioma. Administration of a synthetic peptide targeting the immune checkpoint...

Full description

Bibliographic Details
Main Authors: Michael R. Olin, Elisabet Ampudia-Mesias, Christopher A. Pennell, Aaron Sarver, Clark C. Chen, Christopher L. Moertel, Matthew A. Hunt, G. Elizabeth Pluhar
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Cancers
Subjects:
glioma
immunotherapy
tumor lysate
dogs
Online Access:https://www.mdpi.com/2072-6694/11/2/137

Internet

https://www.mdpi.com/2072-6694/11/2/137

Similar Items