Clinical effects of immunization, bleeding, and albumin-based fluid therapy in horses used as immunoglobulin source to produce a polyspecific antivenom (Echitab-plus-ICP) towards venoms of African snakes

During the production of snake antivenoms, the animals used as immunoglobulin source are subjected to processes that could deteriorate their physical condition. Therefore, these conditions must be carefully designed and validated. In this work, the immunization and bleeding protocols applied to hors...

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Bibliographic Details
Main Authors: Rose Mary Huertas, Mauricio Arguedas, Juan Manuel Estrada, Edwin Moscoso, Deibid Umaña, Gabriela Solano, Mariángela Vargas, Álvaro Segura, Andrés Sánchez, María Herrera, Mauren Villalta, Cynthia Arroyo-Portilla, José María Gutiérrez, Guillermo León
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Toxicon: X
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590171023000103