Long-term weight-loss in gastric bypass patients carrying melanocortin 4 receptor variants.
<h4>Background</h4>The melanocortin 4 receptor (MC4R) critically regulates feeding and satiety. Rare variants in MC4R are predominantly found in obese individuals. Though some rare variants in MC4R discovered in patients have defects in localization, ligand binding and signaling to cAMP,...
Main Authors: | , , , , , , , , , , , |
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פורמט: | Article |
שפה: | English |
יצא לאור: |
Public Library of Science (PLoS)
2014-01-01
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סדרה: | PLoS ONE |
גישה מקוונת: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0093629&type=printable |