Investigation of useful carbon tracers for 13C-metabolic flux analysis of Escherichia coli by considering five experimentally determined flux distributions

The 13C-MFA experiments require an optimal design since the precision or confidence intervals of the estimated flux levels depends on factors such as the composition of 13C-labeled carbon sources, as well as the metabolic flux distribution of interest. In this study, useful compositions of 13C-label...

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Bibliographic Details
Main Authors: Kousuke Maeda, Nobuyuki Okahashi, Yoshihiro Toya, Fumio Matsuda, Hiroshi Shimizu
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Metabolic Engineering Communications
Online Access:http://www.sciencedirect.com/science/article/pii/S2214030116300189