Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex.

The first sequenced marsupial genome promises to reveal unparalleled insights into mammalian evolution. We have used the Monodelphis domestica (gray short-tailed opossum) sequence to construct the first map of a marsupial major histocompatibility complex (MHC). The MHC is the most gene-dense region...

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Bibliographic Details
Main Authors: Katherine Belov, Janine E Deakin, Anthony T Papenfuss, Michelle L Baker, Sandra D Melman, Hannah V Siddle, Nicolas Gouin, David L Goode, Tobias J Sargeant, Mark D Robinson, Matthew J Wakefield, Shaun Mahony, Joseph G R Cross, Panayiotis V Benos, Paul B Samollow, Terence P Speed, Jennifer A Marshall Graves, Robert D Miller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-03-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.0040046