Notch3 regulates ferroptosis via ROS‐induced lipid peroxidation in NSCLC cells

Ferroptosis is type of programmed cell death, which is known to be involved in certain cancers. Notch3 signaling is reported to be involved in the tumorigenesis of non‐small‐cell lung cancer (NSCLC) and regulates iron metabolism, lipid synthesis, and oxidative stress in some tissues. However, whethe...

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Bibliographic Details
Main Authors: Zhikang Li, JinYang Xiao, Mengyu Liu, Jiaqi Cui, Bowen Lian, Yuanlu Sun, Chunyan Li
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.13393