Vitamin B<sub>12</sub> deficiency in the brain leads to DNA hypomethylation in the TCblR/CD320 knockout mouse
<p>Abstract</p> <p>Background</p> <p>DNA methylation is an epigenetic phenomenon that can modulate gene function by up or downregulation of gene expression. Vitamin B<sub>12</sub> and folate pathways are involved in the production of S-Adenosylmethionine, th...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-05-01
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Series: | Nutrition & Metabolism |
Subjects: | |
Online Access: | http://www.nutritionandmetabolism.com/content/9/1/41 |