The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues

The expression of PKM1 and PKM2 in developing, benign, and cancerous prostatic tissues

BackgroundNeuroendocrine prostate cancer (NEPCa) is the most aggressive type of prostate cancer (PCa). However, energy metabolism, one of the hallmarks of cancer, in NEPCa has not been well studied. Pyruvate kinase M (PKM), which catalyzes the final step of glycolysis, has two main splicing isoforms...

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Bibliographic Details
Main Authors: Lin Li, Siyuan Cheng, Yunshin Yeh, Yingli Shi, Nikayla Henderson, David Price, Xin Gu, Xiuping Yu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Oncology
Subjects:
PKM1
PKM2
neuroendocrine
prostate cancer
metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1392085/full

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https://www.frontiersin.org/articles/10.3389/fonc.2024.1392085/full

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