Probiotic lactic acid bacteria alleviate pediatric IBD and remodel gut microbiota by modulating macrophage polarization and suppressing epithelial apoptosis

Probiotic lactic acid bacteria alleviate pediatric IBD and remodel gut microbiota by modulating macrophage polarization and suppressing epithelial apoptosis

IntroductionThe incidence of pediatric inflammatory bowel disease (PIBD) continues to rise. It was reported that the probiotic lactic acid bacteria Pediococcus pentosaceus (P. pentosaceus) can interfere with intestinal immunity, but it is still unknown whether it can alleviate PIBD and the concrete...

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Bibliographic Details
Main Authors: Huiying Hua, Chun Pan, Xixi Chen, Mengxia Jing, Jinfang Xie, Yuanqi Gao, Jiebin Huang, Xuehua Chen, Yujing Gao, Chundi Xu, Pu Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Microbiology
Subjects:
pediatric IBD
macrophage polarization
intestinal epithelium apoptosis
Akkermansia muciniphila
Pediococcus pentosaceus CECT8330
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2023.1168924/full

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https://www.frontiersin.org/articles/10.3389/fmicb.2023.1168924/full

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