The Fur-like regulatory protein MAP3773c modulates key metabolic pathways in Mycobacterium avium subsp. paratuberculosis under in-vitro iron starvation

Abstract Johne’s disease (JD) is a chronic enteric infection of dairy cattle worldwide. Mycobacterium avium subsp. paratuberculosis (MAP), the causative agent of JD, is fastidious often requiring eight to sixteen weeks to produce colonies in culture—a major hurdle in the diagnosis and therefore in i...

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Bibliographic Details
Main Authors: Sajani Thapa, Govardhan Rathnaiah, Denise K. Zinniel, Raul G. Barletta, John P. Bannantine, Marianne Huebner, Srinand Sreevatsan
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-024-59691-3