Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors

Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long-term in vitro or persistent in vivo infection, th...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Dalibor Miklík, Filip Šenigl, Jiří Hejnar
التنسيق: مقال
اللغة:English
منشور في: MDPI AG 2018-03-01
سلاسل:Viruses
الموضوعات:
الوصول للمادة أونلاين:http://www.mdpi.com/1999-4915/10/3/116