Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors

Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long-term in vitro or persistent in vivo infection, th...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Dalibor Miklík, Filip Šenigl, Jiří Hejnar
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2018-03-01
Schriftenreihe:Viruses
Schlagworte:
Online Zugang:http://www.mdpi.com/1999-4915/10/3/116