Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors
Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long-term in vitro or persistent in vivo infection, th...
Hauptverfasser: | , , |
---|---|
Format: | Artikel |
Sprache: | English |
Veröffentlicht: |
MDPI AG
2018-03-01
|
Schriftenreihe: | Viruses |
Schlagworte: | |
Online Zugang: | http://www.mdpi.com/1999-4915/10/3/116 |