Proviruses with Long-Term Stable Expression Accumulate in Transcriptionally Active Chromatin Close to the Gene Regulatory Elements: Comparison of ASLV-, HIV- and MLV-Derived Vectors
Individual groups of retroviruses and retroviral vectors differ in their integration site preference and interaction with the host genome. Hence, immediately after infection genome-wide distribution of integrated proviruses is non-random. During long-term in vitro or persistent in vivo infection, th...
| Main Authors: | , , |
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| 格式: | Article |
| 語言: | English |
| 出版: |
MDPI AG
2018-03-01
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| 叢編: | Viruses |
| 主題: | |
| 在線閱讀: | http://www.mdpi.com/1999-4915/10/3/116 |