MIEAP and ATG5 are tumor suppressors in a mouse model of BRAFV600E-positive thyroid cancer

Mitochondria-eating protein (MIEAP) is a molecule important for non-canonical mitophagy and thought to be a tumor suppressor. Our previous study found that MIEAP expression is defective in thyroid oncocytomas, irrespective of being benign or malignant, and also in non-oncocytic thyroid cancers. Thyr...

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Bibliographic Details
Main Authors: Koichiro Hamada, Tomomi Kurashige, Mika Shimamura, Hirofumi Arakawa, Yasuyuki Nakamura, Yuji Nagayama
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.932754/full