Hats off to 20S proteasome substrate discovery
Uncapped free 20S proteasomes are abundant and active in cells, and yet their degraded intracellular protein substrates have remained underexplored. In their recent study, Sharon and colleagues (Pepelnjak et al, 2024) developed an advanced proteomics method (PiP-MS) to comprehensively explore 20S pr...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2024-03-01
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Series: | Molecular Systems Biology |
Online Access: | https://doi.org/10.1038/s44320-024-00028-7 |