A potential role of autophagy-mediated vascular senescence in the pathophysiology of HFpEF

A potential role of autophagy-mediated vascular senescence in the pathophysiology of HFpEF

Heart failure with preserved ejection fraction (HFpEF) is one of the most complex and most prevalent cardiometabolic diseases in aging population. Age, obesity, diabetes, and hypertension are the main comorbidities of HFpEF. Microvascular dysfunction and vascular remodeling play a major role in its...

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Bibliographic Details
Main Authors: Fernanda Sanhueza-Olivares, Mayarling F. Troncoso, Francisco Pino-de la Fuente, Javiera Martinez-Bilbao, Jaime A. Riquelme, Ignacio Norambuena-Soto, Monica Villa, Sergio Lavandero, Pablo F. Castro, Mario Chiong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-11-01
Series:Frontiers in Endocrinology
Subjects:
autophagy
HFpEF - heart failure with preserved ejection fraction
vascular senescence
vascular aging
obesity
diabetes
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1057349/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1057349/full

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