A light-gated transcriptional recorder for detecting cell-cell contacts

A light-gated transcriptional recorder for detecting cell-cell contacts

Technologies for detecting cell-cell contacts are powerful tools for studying a wide range of biological processes, from neuronal signaling to cancer-immune interactions within the tumor microenvironment. Here, we report TRACC (Transcriptional Readout Activated by Cell-cell Contacts), a GPCR-based t...

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Bibliographic Details
Main Authors: Kelvin F Cho, Shawn M Gillespie, Nicholas A Kalogriopoulos, Michael A Quezada, Martin Jacko, Michelle Monje, Alice Y Ting
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-03-01
Series:eLife
Subjects:
synthetic biology
cell contacts
transcriptional reporter
Online Access:https://elifesciences.org/articles/70881

Internet

https://elifesciences.org/articles/70881

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