The possible correlation between serum GRB2 levels and carotid atherosclerosis in patients with type 2 diabetes mellitus

The possible correlation between serum GRB2 levels and carotid atherosclerosis in patients with type 2 diabetes mellitus

Background and purposeGrowth factor receptor-bound protein 2(GRB2), a bridging protein. An animal study showed that downregulation of GRB2 inhibited the activation of PI3K/AKT/NF-kB pathway which improved lipid accumulation and inflammatory infiltration in rats with atherosclerosis (AS), resulting i...

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Bibliographic Details
Main Authors: Yuyan Dong, Juxiang Liu, Jing Ma, Jinxing Quan, Yanxia Bao, Yaqiang Cui
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Endocrinology
Subjects:
serum GRB2 levels
inflammatory
glycolipid metabolism
type 2 diabetes mellitus
carotid atherosclerosis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.963191/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.963191/full

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