Vitamin D/vitamin D receptor/Atg16L1 axis maintains podocyte autophagy and survival in diabetic kidney disease

Vitamin D/vitamin D receptor/Atg16L1 axis maintains podocyte autophagy and survival in diabetic kidney disease

Objective To investigate the effect of vitamin D/vitamin D receptor (VDR)/Atg16L1 signaling on podocyte autophagy and survival in diabetic nephropathy.Methods Diabetic rat models were induced by intraperitoneal injection of streptozotocin (STZ) (60 mg/kg) and treated with and without gavage of 0.1 μ...

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Bibliographic Details
Main Authors: Lang Shi, Chao Xiao, Yafei Zhang, Yao Xia, Hongchu Zha, Jiefu Zhu, Zhixia Song
Format: Article
Language:English
Published: Taylor & Francis Group 2022-12-01
Series:Renal Failure
Subjects:
aVitD3
diabetic nephropathy
podocyte
autophagy
VDR/Atg16L1 axis
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2022.2063744

Internet

https://www.tandfonline.com/doi/10.1080/0886022X.2022.2063744

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