3D Super-Resolution Nuclear Q-FISH Imaging Reveals Cell-Cycle-Related Telomere Changes

3D Super-Resolution Nuclear Q-FISH Imaging Reveals Cell-Cycle-Related Telomere Changes

We present novel workflows for Q-FISH nanoscopy with the potential for prognostic applications and resolving novel chromatin compaction changes. DNA-fluorescence in situ hybridization (DNA-FISH) is a routine application to visualize telomeres, repetitive terminal DNA sequences, in cells and tissues....

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Bibliographic Details
Main Authors: Tatiana V. Pochechueva, Niko Schwenzer, Tobias Kohl, Sören Brandenburg, Gesa Kaltenecker, Bernd Wollnik, Stephan E. Lehnart
Format: Article
Language:English
Published: MDPI AG 2024-03-01
Series:International Journal of Molecular Sciences
Subjects:
telomere Q-FISH
super-resolution STED nanoscopy
DyMIN modality
HeLa
cardiac myocyte
Online Access:https://www.mdpi.com/1422-0067/25/6/3183

Internet

https://www.mdpi.com/1422-0067/25/6/3183

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