MiR-26a-5p from HucMSC-derived extracellular vesicles inhibits epithelial mesenchymal transition by targeting Adam17 in silica-induced lung fibrosis

MiR-26a-5p from HucMSC-derived extracellular vesicles inhibits epithelial mesenchymal transition by targeting Adam17 in silica-induced lung fibrosis

Silicosis is one of several potentially fatal occupational pathologies caused by the prolonged inhalation of respirable crystalline silica. Previous studies have shown that lung epithelial-mesenchymal transition (EMT) plays a significant role in the fibrosis effect of silicosis. Human umbilical cord...

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Bibliographic Details
Main Authors: Jing Zhao, Qiyue Jiang, Chunjie Xu, Qiyue Jia, Hongwei Wang, Wenming Xue, Yan Wang, Zhonghui Zhu, Lin Tian
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Silica
HucMSC-EVs
EMT
MiR-26a-5p
Adam17
Lung fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323004542

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http://www.sciencedirect.com/science/article/pii/S0147651323004542

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