Identification of the Lipodepsipeptide MDN-0066, a Novel Inhibitor of VHL/HIF Pathway Produced by a New Pseudomonas Species.

Throughout recent history, metabolites of microbial origin have had an extraordinary impact on the welfare of humanity. In fact, natural products have largely been--and still are--considered an exceedingly valuable platform for the discovery of new drugs against diverse pathologies. Such value is pa...

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Bibliographic Details
Main Authors: Bastien Cautain, Nuria de Pedro, Christian Schulz, Javier Pascual, Thiciana da S Sousa, Jesús Martin, Ignacio Pérez-Victoria, Francisco Asensio, Ignacio González, Gerald F Bills, Fernando Reyes, Olga Genilloud, Francisca Vicente
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0125221